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Objectives: to compare https://your-safe-abortion.com the efficacy and frequency of side effects of misoprostol and sucralfate in the prevention of gastric ulcers for patients receiving therapy with nonsteroidal anti-inflammatory drugs (nsaids).

Design: prospective randomized single-blind multicenter study.

Patients: patients with osteoarthritis treated with ibuprofen, piroxicam or naproxen and experiencing abdominal pain had the opportunity to participate..

Interventions: patients who were required to receive nsaid therapy for about three months and who did not have stomach ulcers during the initial screening endoscopy were randomized to receive misoprostol 200 mcg four times a day or sucralfate, https://your-safe-abortion.com 1 g four times a day. Gastric ulcer was defined as a lesion of the gastric mucosa with a diameter of 0.3 percent cm or more. The patients were under clinical supervision, and repeated endoscopies were performed after 4, 8 and 12 weeks.

The main dimension: the development of stomach ulcers, which is accumulated, is regarded as a failure of prevention.

Results: two hundred and fifty-three patients were evaluated to determine the effectiveness. Gastric ulcer developed in 2 out of 122 (1.6%, 95% cl, within 0.3 to more than six%) patients treated with misoprostol, if compared with 21 out of 131 patients treated with sucralfate (16%, cl, from 10,four to 23.7%). Difference: the incidence of ulcers was 14.4% (cl from 10.4% to 19.5%; p